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Új, 3,4-diszubsztituált pirrolin nitroxidok szintézise és alkalmazása
(2018-10-09)
A Pécsi Tudományegyetem Szerves és Gyógyszerkémiai Intézetében csaknem 60 éve végeznek
tudományos kutatómunkát a heterociklusos szerves vegyületek területén. Az 1970-es években
Dr. Hideg Kálmán a néhai Prof. Tigyi József ...
Fej-nyaki daganatok mikrokörnyezetének molekuláris vizsgálata
(2018-03-13)
More than 90% of head and neck cancers are squamous cell cancers with a 5-year survival rate of only around 60%. Tumors are often diagnosed in an advanced stage due to the lack of specific symptoms and diagnostic difficulties. ...
Gyulladás és oxidatív stressz hatása jelátviteli folyamatokra és membránrendszerek stabilitására
(2018-10-09)
Toll-Like Receptor 4 (TLR4) plays an important role in initiating the innate immune response and its activation by the bacterial cell wall component endotoxin (lipopolysaccharide (LPS)) is responsible for chronic and acute ...
Structural Dynamics and Physiological Processes of Actin Filament Length Regulator Proteins
(2018-10-09)
Actin is a 42 kDa globular protein. Actin forms microfilaments in eukaryotic cells that are the major component of the cytoskeletal system. In muscle cells, actin filaments are the main component of thin filaments and work ...
A nukleotidok és az aktinkötő fehérjék szerepe az aktin funkcionális konformációváltozásaiban
(2018-12-04)
Actin is one of the main component in eukaryote cells which plays significant role in many cellular processes, like force-generation, maintenance of the shape of cells, celldivision cycle, and transport processes. Many ...
Coordination of Actin and Microtubule Dynamics by the Formin Protein Dishevelled-associated Activator of Morphogenesis
(2018-10-09)
Essential components of the eukaryotic cells are the polymer networks built from protein subunits; including microfilaments (or actin filaments, AF), intermediate filaments (IF) and microtubules (MT). These cytoskeletal ...