Any form of trauma, including surgery, is known to result in oxidative stress. Increased intra-abdominal pressure during pneumoperitoneum and inflation-deflation may cause ischemia reperfusion and, so, oxidative stress may ...

A modern prevenciós szemlélet terjedésével, az egyik leggyakrabban alkalmazott gyógyszer a vérlemezke-aggregációgátlók csoportjába tartozik. A kezelés ellenére fennálló magas reziduális vérlemezke-reaktivitás (HRPR= high ...

According to international statistics, CRC is one of the leading cause of death both in the USA and Europe (14-15 % of all tumors). They have already been mentioned in the literature as the disaster of the western (welfare) ...

In 1882 Cohnheim postulated that “ein Fehler, eine Unregelmässigkeit der embryonalen Anlage ist, in der die eigentliche Ursache der späteren Geschwulst gesucht werden muss”, e.g. an error and impaired regulation in embryonic ...

Pituitary adenylate cyclase activating polypeptide (PACAP) is a widely distributed neuropeptide, first isolated from hypothalamic extracts. PACAP belongs to the vasoactive intestinal peptide (VIP)/secretin/glucagon peptide ...

O-glycosylation is a dynamic, reversible protein post-translational modification which modulates the metabolic state of cells. It interacts with several other post-translational modifications including acetylation, ...

The spine is a harmonic system of vertebrae joint together like a column, forming a stable but sufficiently mobile frame whose main function is the protection of the spinal cord, bearing of the body’s burdens and enabling ...

Diagnosis of sepsis still remains one of the major challenges in medicine. Global estimates suggest 19 million hospitalized individuals with sepsis per year. Since sepsis is a multifaceted syndrome rather than a disease, ...

Arterial hypertension represents a major cardiovascular epidemic condition, with a prevalence of more than 25% throughout the adult population, affecting nearly one billion individuals around the globe. It remains ...

There are few methods available for assessing the well-being of the fetus in utero. Examining the frequency of fetal heart rate: cardiotocography (CTG) is essential in daily obstetric practice, however, the sensitivity and ...