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A proprioceptív rendszer multimodális integrációs zavara a testséma - testkép összefüggéseiben Parkinson-kórban
(2018-12-04)
The most common definition of kinesthesia could be described as the awareness of the body’s and the limbs’ position and movement in space. A disorder of kinesthesia is especially typical of Parkinson’s. We use the term, ...
PACAP (hipofízis adenilát-cikláz aktiváló polipeptid) fogfejlődésre gyakorolt hatásainak vizsgálata állatmodellen
(2018-04-24)
Pituitary adenylate cyclase activating polypeptide (PACAP) is a multifunctional neuropeptide with widespread distribution. It was first isolated from ovine hypothalamic extract on the basis of its ability to stimulate cAMP ...
Glukokortikoid-indukált apoptózis vizsgálata éretlen és érett T sejt alcsoportokban
(2019-01-22)
Glucocorticoid hormones (GC) are produced by the cells of zona fasciculata in the adrenal gland. The most important GC in human is cortisol, in murine the corticosterone. The release of the hormones is strictly regulated ...
Regulatórikus T-sejtek glukokortikoid hormon érzékenységének modell vizsgálata és eltérései szisztémás szklerózisban
(2018-06-05)
Regulatory T cells (Treg) are a specialized subpopulation of T cells that play a key role in maintaining tolerance to self-antigens and in suppression of excessive immune response after antigenic stimulation, thereby helping ...
Early Life Adversity in the Rodent Neurobehavioral Development and Three Hit Concept Model of Major Depressive Disorder
(2018-06-05)
Depression is a major burden on the affected person, on the immediate and extended family and the society as well. The great weight caused by the disease can be detected on families, on the extended society and more ...
Merre tartanak a jövő orvosai?
(2018-10-09)
The operability and quality of health care rely mostly on the professionals working in its branches, therefore it is crucial to gain present and future connected information about the human resources in health care. Among ...
A ZAP-70 kináz hiányának vizsgálata in vivo T-sejt aktivációban, differenciációban és autoimmun arthritis kialakulásában
(2019-10-15)
The zeta-chain associated protein of 70 kDa (ZAP-70) was first described by Chan and colleagues in Jurkat cells stimulated through the T cell receptor. Under physiological conditions ZAP-70 is expressed by T cells and NK ...
A mediális prefrontális kéreg szerepe az auditoros szenzoros-motoros kapuzó mechanizmusban
(2019-12-03)
The limited information processing capacity of the central nervous system makes it necessary to prevent the entry of irrelevant stimuli into the higher neurological centres. To achieve this, a number of mechanisms have ...
Az NKX2-3 transzkripciós faktor szerepe a bél-asszociált nyirokszövetek veleszületett limfoid sejt-megoszlásának és a gyulladásos bélbetegségek lefolyásának szabályozásában
(2019-12-03)
Inflammatory bowel disease (IBD) is one of the most common chronic inflammatory diseases of the gut. We can distinguish two main types of IBD: Crohn’s disease (CD) and ulcerative colitis (UC). Several people are affected ...
A gyermekkori disztális orsócsont törés kezelési lehetőségeinek retrospektív- és a csontgyógyulás vizsgálata állatkísérletes modellen
(2019-12-03)
Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide with widespread occurrence in various organs and diverse effects both in the nervous system and in the periphery. PACAP is strongly expressed in ...