Szén-monoxid és szén-monoxid analógok beékelődési reakciói: Elméleti és szintetikus tanulmány

Abstract

The reactions, which based on the application of organometallic compounds, areimportant in synthetic organic chemistry. Organometallic reagents in homogeneouscatalytic reactions open the possibility for synthetic applications which had not beenfeasible in the classical ways. One prominent example for homogeneous catalytictransformations is the activation of small molecules by insertion into metal-carbonbond. The most important field of application of the carbonyl complexes is thecarbonyl group insertion into organic molecules leading to the formation of newcarbon-carbon or carbon-heteroatom bonds. Carbonyl compounds and carboxylicacid derivatives can be produced with carbon monoxide insertion in laboratory or inindustrial processes. In this way, important intermediates or products of thepharmaceutical, paint and pesticide industries can be synthesised. The molecules, which contain the amidine functional group, are remarkable inseveral fields in the synthetic organic chemistry and are of special importance in theproduction of biologically active products. Regarding the biological importance ofnucleobases, it is not surprising, that amidine-based compounds can be considered asbasic elements of pharmaceutical chemistry and the above mentioned structureoccurs in numerous agents. Recently, transition metal complexes of heterocumulene molecules wereinvestigated widely in recent decades and it was determined that carbon dioxide,sulfur dioxide and carbonyl sulfide can be activated by transition metals. Thesemolecules can react in insertion, dimerisation and disproportionation reactions.Unraveling the coordination features of small molecules can lead us toinvaluable knowledge paving the way for the development of effective catalyticsystems with high activity and selectivity. Theoretical methods are especiallysuitable to describe the donor-acceptor interactions as well as steric and electronicproperties of various ligands in transition metal complexes.