Since the treatment of neuropathic pain and the neurogenic components of the inflammatory processes is an unresolved problem due to a grate range of severe side effect and the presently available drug groups cannot be ...

Coffea species are well-known and widespread all over the world. They have an important role in science because of their pharmacological role. They provide one of the most sought products after petrol on the international ...

János Selye defined the classic concept of stress as a „nonspecific response of the body to any threatening demand” (1936). More recently, McEwen (2000) defined stress as a real or interpreted threat to the physiological ...

The Internet has revolutionized and changed our lives, communication and procurement practices and strategies. As the access to the Internet is increasing, the use of Internet to seek health information is also expending. ...

Obesity, as a common risk factor for numerous diseases became in the last decades a major epidemiological and general healthcare challenge in Western countries. While middle-aged populations tend to become obese, old age ...

Raynaud’s phenomenon, acrocyanosis and erythromelalgia are functional vascular diseases that differ with respect to clinical signs, prevalence, pathogenesis, therapy and prognosis. The most common form is Raynaud phenomenon. ...

During the past decades, prevalence of metabolic disorders increased dramatically in populations all over the world. Both energy excess (e.g. obesity) and deficit (e.g. cachexia, sarcopenia) are important worldwide challenges ...

Abnormalities of energy balance present major public health problems with rapidly increasing prevalence. They include changes of body weight (BW) and/or body composition. Obesity is defined as excessive accumulation of ...

Chronic rhinosinusitis (CRS) is multifactorial and characterized by chronic inflammation of the sinonasal mucosa and its exact ethiology is still unclear. The limitations of earlier assumptions about CRS that it is an ...

The Transient Receptor Potential Ankyrin 1 (TRPA1) and Vanilloid 1 (TRPV1) are non-selective cation channels predominantly localized on capsaicin-sensitive peptidergic sensory neurons and mediate pain and inflammation. ...