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PACAP (hipofízis adenilát-cikláz aktiváló polipeptid) fogfejlődésre gyakorolt hatásainak vizsgálata állatmodellen
(2018-04-24)
Pituitary adenylate cyclase activating polypeptide (PACAP) is a multifunctional neuropeptide with widespread distribution. It was first isolated from ovine hypothalamic extract on the basis of its ability to stimulate cAMP ...
Anesztetikus prekondícionálás és a VIP/PACAP peptidcsalád védő szerepének vizsgálata iszkémiás retinopátiában
(2018-04-24)
Pituitary adenylate cyclase activating polypeptide (PACAP) is a widely distributed neuropeptide, first isolated from hypothalamic extracts. PACAP belongs to the vasoactive intestinal peptide (VIP)/secretin/glucagon peptide ...
Pharmacological PARP-1 Inhibition Against Hypertensive Target Organ Damage in a Chronic Animal Model
(2018-03-13)
Arterial hypertension represents a major cardiovascular epidemic condition,
with a prevalence of more than 25% throughout the adult population, affecting nearly
one billion individuals around the globe. It remains ...
Azonosító és kereső kutyák kriminalisztikai alkalmazása
(2018-04-24)
A kutya kriminalisztika hasznosítása mind a felderítés, mind a bizonyítás körében értelmezhető. A kriminálkinológia vagy kriminalisztikai odorológia tudományát régóta művelik Magyarországon is, azonban összefoglaló monográfia ...
Hipofízis adenilát-cikláz aktiváló polipeptid génhiányos egerek stresszadaptációs rendszereinek vizsgálata akut és krónikus modellekben
(2018-03-13)
János Selye defined the classic concept of stress as a „nonspecific response of the body to any threatening demand” (1936). More recently, McEwen (2000) defined stress as a real or interpreted threat to the physiological ...
Fej-nyaki daganatok mikrokörnyezetének molekuláris vizsgálata
(2018-03-13)
More than 90% of head and neck cancers are squamous cell cancers with a 5-year survival rate of only around 60%. Tumors are often diagnosed in an advanced stage due to the lack of specific symptoms and diagnostic difficulties. ...
Regulatórikus T-sejtek glukokortikoid hormon érzékenységének modell vizsgálata és eltérései szisztémás szklerózisban
(2018-06-05)
Regulatory T cells (Treg) are a specialized subpopulation of T cells that play a key role in maintaining tolerance to self-antigens and in suppression of excessive immune response after antigenic stimulation, thereby helping ...
Advanced Imaging in Traumatic Brain Injury
(2018-01-23)
Traumatic brain injury (TBI) constitutes a public health problem worldwide, because of its high incidence, morbidity and mortality. TBI is a leading cause of death and disability in the young, otherwise healthy, employed ...
Early Life Adversity in the Rodent Neurobehavioral Development and Three Hit Concept Model of Major Depressive Disorder
(2018-06-05)
Depression is a major burden on the affected person, on the immediate and extended family and the society as well. The great weight caused by the disease can be detected on families, on the extended society and more ...
Elektrofiziológia a szülészetben
(2018-10-09)
There are few methods available for assessing the well-being of the fetus in utero. Examining the frequency of fetal heart rate: cardiotocography (CTG) is essential in daily obstetric practice, however, the sensitivity and ...